| Journal Call no. | R644.H63J573 |
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| Author | Lee, C. H. |
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| Article Title | Antithyroid drug : induced agranulocytosis / C.H. Lee and R.H.S. Liang. |
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| Is Part Of | Hong Kong medical journal ; v.5, no.4, Dec 1999, p.394-396. |
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| Abstract | Thyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis. The article reports on two patients with antithyroid drug-induced agranulocytosis. Both patients presented with fever and severe neutropenia. The administration of granulocyte colony-stimulating factor resulted in a dramatic improvement in the white blood cell count and symptoms. Antithyroid drug-induced agranulocytosis is a potentially lethal condition but is completely reversible when recognised early and when prompt treatment is offered. |
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