PolyU Library
Journal Call no.RC681.A2H65
AuthorThomas, G. N.
Article TitleMethylenetetrahydrofolate reductase (MTHFR) gene polymorphism contributes to variation in fasting homocysteine levels (Hcy) in Chinese / GN Thomas ... [et al.].
Is Part OfHong Kong College of Cardiology ... Annual Scientific Congress : proceedings ; 1997, p.218.
AbstractHyperhomocysteinaemia has recently been identified as an independent risk factor for coronary heart disease (CHD). This is the abstract of a study in Hong Kong Chinese with angiographically confirmed CHD where significantly higher fasting homocysteine levels (Hcy) compared to controls are showed. Although controversial, some investigators have found that the variant T allele of the methylenehydrofolate reductase (MTHFR) gene is responsible for a 50% reduction in enzyme activity and high Hcy.