| Journal Call no. | R644.H63J573 |
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| Author | Leung, P. |
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| Article Title | N-ras mutations in myelodysplastic syndromes in Hong Kong Chinese / P Leung, LC Chan and R Liang. |
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| Is Part Of | Hong Kong medical journal ; v.1, no.4, Dec 1995, p.290-294, illus. |
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| Abstract | Hong Kong Chinese patients with myelodysplastic syndromes were screened for the presence of N-ras mutation by using the polymerase chain reaction/dot blot hybridization techinque. In a patient, mutant N-ras was detected in a follow up sample taken two months later, although there was no change in the blast percentage compared with the presentation sample. Our study showed that N-ras mutation is an infrequent finding in Hong Kong Chinese myelodysplastic syndrome patients. An N-ras mutation is not necessarily accompained by an alteration in the haematological picture. |
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